Molecular Formula | C11H20N2O2 |
Molar Mass | 212.29 |
Density | 1.10 |
Boling Point | 301.3±35.0 °C(Predicted) |
Flash Point | 136°C |
Vapor Presure | 0.00106mmHg at 25°C |
pKa | 10?+-.0.20(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
Refractive Index | 1.521 |
Hazard Class | IRRITANT |
Introduction | piperazine and morpholine are common structural fragments in small molecule drugs, as its analogs, 6-diazaspiro [3,4] cyclooctane derivatives have good application prospects in the field of pharmaceutical chemistry. Tert-butyl 2, 6-diazotifen [3.4] octane -6-carboxylate is a common intermediate in chemical synthesis. |
Use | with tert-butyl 2, 6-diazotifen [3.4] octane -6-carboxylate as a reagent to synthesize spirodiamine-diarylketone oxime derivatives as melanin concentrating hormone (MCH-1R) antagonists; it is also useful as a reagent for the synthesis of dihydroisoindole carboxamide derivatives as NAMPT and ROCK inhibitors. |